Extracellular vesicle-derived CircWhsc1 promotes cardiomyocyte proliferation and heart repair by activating TRIM59/STAT3/Cyclin B2 pathway

INTRODUCTION: Extracellular vesicles (EVs)-mediated cell-to-cell communication is crucial for hypoxia-induced cell proliferation and tissue repair, but its function in endogenous cardiac regeneration is still unknown. OBJECTIVES: Herein, we aimed to determine whether hypoxia-inducible circWhsc1 in e...

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Detalles Bibliográficos
Autores principales: Wei, Guoquan, Li, Chuling, Jia, Xiaoqian, Xie, Jingfang, Tang, Zhenquan, Jin, Ming, Chen, Qiqi, Sun, Yili, He, Sisi, Li, Xinzhong, Chen, Yanmei, Zheng, Hao, Liao, Wangjun, Liao, Yulin, Bin, Jianping, Huang, Senlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658329/
https://www.ncbi.nlm.nih.gov/pubmed/36587763
http://dx.doi.org/10.1016/j.jare.2022.12.014

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