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No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan‐induced inhibition of platelet aggregation response
BACKGROUND: A variant in the canine phosphodiesterase (PDE) 5A gene (PDE5A:E90K) is associated with decreased concentrations of circulating cyclic guanosine monophosphate (cGMP) and response to PDE5 inhibitor treatment. Pimobendan is a PDE inhibitor recommended for medical treatment of certain stage...
Autores principales: | Reimann, Maria J., Faisst, Daniel N., Knold, Mads, Meurs, Kathryn M., Stern, Joshua A., Cremer, Signe E., Møller, Jacob E., Ljungvall, Ingrid, Häggström, Jens, Olsen, Lisbeth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658480/ https://www.ncbi.nlm.nih.gov/pubmed/37743723 http://dx.doi.org/10.1111/jvim.16871 |
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