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Pharmacokinetics and pharmacodynamics of intranasal and intramuscular administration of naloxone in working dogs administered fentanyl

BACKGROUND: Working dogs exposed to narcotics might require reversal in the field. OBJECTIVE: To explore the pharmacokinetic and pharmacodynamic effects of naloxone administered intramuscularly (IM) or intranasally (IN) to reverse fentanyl sedation in working dogs. ANIMALS: Ten healthy, working dogs...

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Detalles Bibliográficos
Autores principales: Barr, Ciara A., Haughan, Joanne, Gianotti, Giacomo, Varner, Kelley, Drobatz, Kenneth J., Stefanovski, Darko, Robinson, Mary, Pennington, Mark, McGuire, Amanda, Otto, Cynthia M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658493/
https://www.ncbi.nlm.nih.gov/pubmed/37861360
http://dx.doi.org/10.1111/jvim.16901

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