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Oral cytarabine ocfosfate pharmacokinetics and assessment of leukocyte biomarkers in normal dogs

BACKGROUND: Cytosine arabinoside (Ara‐C) is a nucleoside analog prodrug utilized for immunomodulatory effects mediated by its active metabolite Ara‐CTP. Optimal dosing protocols for immunomodulation in dogs have not been defined. Cytarabine ocfosfate (CO) is a lipophilic prodrug of Ara‐C that can be...

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Detalles Bibliográficos
Autores principales:	Zwueste, Danielle M., Vernau, Karen M., Vernau, William, Pypendop, Bruno H., Knych, Heather K., Rodrigues, Carlos A., Kol, Amir, Questa, Maria, Dickinson, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2023
Materias:	SMALL ANIMAL
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658504/ https://www.ncbi.nlm.nih.gov/pubmed/37670479 http://dx.doi.org/10.1111/jvim.16842

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