IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells

INTRODUCTION: Inflammation plays a significant role in various cancers, including lung cancer, where the inflammatory cytokine IL-1β is often elevated in the tumor microenvironment. Patients with lung adenocarcinoma show higher levels of serum IL-1β compared to healthy individual. Moreover, IL-1β bl...

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Detalles Bibliográficos
Autores principales: Nawas, Afshan Fathima, Solmonson, Ashley, Gao, Boning, DeBerardinis, Ralph J., Minna, John D., Conacci-Sorrell, Maralice, Mendelson, Carole R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658741/
https://www.ncbi.nlm.nih.gov/pubmed/37985999
http://dx.doi.org/10.1186/s12964-023-01348-1

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