Cellular reprogramming is driven by widespread rewiring of promoter-enhancer interactions

BACKGROUND: Long-range interactions between promoters and cis-regulatory elements, such as enhancers, play critical roles in gene regulation. However, the role of three-dimensional (3D) chromatin structure in orchestrating changes in transcriptional regulation during direct cell reprogramming is not...

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Detalles Bibliográficos
Autores principales: Wang, Miao, He, Bing, Hao, Yueling, Srinivasan, Divyaa, Shrinet, Jatin, Fraser, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658794/
https://www.ncbi.nlm.nih.gov/pubmed/37981682
http://dx.doi.org/10.1186/s12915-023-01766-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658794/
https://www.ncbi.nlm.nih.gov/pubmed/37981682
http://dx.doi.org/10.1186/s12915-023-01766-0

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