Concurrent Targeting of HDAC and PI3K to Overcome Phenotypic Heterogeneity of Castration-resistant and Neuroendocrine Prostate Cancers

Castration-resistant prostate cancer (CRPC) consists of multiple phenotypic subtypes including androgen receptor (AR)-active prostate cancer (ARPC) and neuroendocrine prostate cancer (NEPC). Tumor cells with these phenotypes can coexist between metastases within a patient and within an individual tu...

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Detalles Bibliográficos
Autores principales: Zhang, Ailin, Lau, Nathan A., Wong, Alicia, Brown, Lisha G., Coleman, Ilsa M., De Sarkar, Navonil, Li, Dapei, DeLucia, Diana C., Labrecque, Mark P., Nguyen, Holly M., Conner, Jennifer L., Dumpit, Ruth F., True, Lawrence D., Lin, Daniel W., Corey, Eva, Alumkal, Joshi J., Nelson, Peter S., Morrissey, Colm, Lee, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658857/
https://www.ncbi.nlm.nih.gov/pubmed/37823778
http://dx.doi.org/10.1158/2767-9764.CRC-23-0250

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