Overexpression of ZNF488 supports pancreatic cancer cell proliferation and tumorigenesis through inhibition of ferroptosis via regulating SCD1-mediated unsaturated fatty acid metabolism

BACKGROUND: Pancreatic cancer is a malignancy with high mortality. Once diagnosed, effective treatment strategies are limited and the five-year survival is extremely poor. Recent studies have shown that zinc finger proteins play important roles in tumorigenesis, including pancreatic cancer. However,...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Qifeng, Lan, Zhongmin, Zhang, Shuisheng, Ren, Hu, Wang, Shunda, Wang, Peng, Feng, Lin, Li, Dan, Wang, Chengfeng, Bai, Xiaofeng, Zhang, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10658979/
https://www.ncbi.nlm.nih.gov/pubmed/37986084
http://dx.doi.org/10.1186/s13062-023-00421-6

Ejemplares similares

Ejemplares similares