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HIF-1α promotes kidney organoid vascularization and applications in disease modeling
BACKGROUND: Kidney organoids derived from human pluripotent stem cells (HiPSCs) hold huge applications for drug screening, disease modeling, and cell transplanting therapy. However, these applications are limited since kidney organoid cannot maintain complete morphology and function like human kidne...
Autores principales: | Peng, Kexin, Xie, Wanqin, Wang, Tingting, Li, Yamei, de Dieu Habimana, Jean, Amissah, Obed Boadi, Huang, Jufang, Chen, Yong, Ni, Bin, Li, Zhiyuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659095/ https://www.ncbi.nlm.nih.gov/pubmed/37981699 http://dx.doi.org/10.1186/s13287-023-03528-9 |
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