NK cell-induced damage to P.falciparum-infected erythrocytes requires ligand-specific recognition and releases parasitophorous vacuoles that are phagocytosed by monocytes in the presence of immune IgG

Natural killer (NK) cells lyse virus-infected cells and transformed cells through polarized delivery of lytic effector molecules into target cells. We have shown that NK cells lyse Plasmodium falciparum-infected red blood cells (iRBC) via antibody-dependent cellular cytotoxicity (ADCC). A high frequ...

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Detalles Bibliográficos
Autores principales: Sekar, Padmapriya, Rajagopalan, Sumati, Shabani, Estela, Kanjee, Usheer, Schureck, Marc A., Arora, Gunjan, Peterson, Mary E., Traore, Boubacar, Crompton, Peter D., Duraisingh, Manoj T., Desai, Sanjay A., Long, Eric O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659167/
https://www.ncbi.nlm.nih.gov/pubmed/37939134
http://dx.doi.org/10.1371/journal.ppat.1011585

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