The pH of Drinking Water and Its Effect on the pH of Urine

Aim: The aim was to determine whether urine pH changed or not with different pH values of drinking water. With the results obtained from animal studies, comments can be made about the effect of water with different pH levels that people drink on kidney stones. Method: A total of 24 Wistar Albino rats were divided into three groups containing eight rats each: the first group was given water with pH 5.5, the second group was given water with pH 7 and the third group was given water with pH 8.2 in the same environment and conditions during 13 days. All rats consumed water in line with their natural feeding habits. All rats had urine pH measurements performed and recorded every day at the same time. The groups were later compared in terms of daily pH values. Results: When daily urine pH values were compared, there were statistically significant differences between pH measurements on the first, fourth and seventh day (p=0.02, p=0.017 and p=0.007, respectively). When first-day values are compared with post-hoc analyses, the urine pH in Group 2 was identified to be lower compared to Group 1 and Group 3 (p<0.001). When the fourth-day values were assessed, the urine pH of Group 2 was observed to be higher than Group 1 and Group 3 (p<0.001). On the seventh day, Group 3 had higher urine pH compared to the other groups (p<0.001). Conclusion: The variation in drinking water pH does not directly change urine pH; however, it causes a change in the urine pH on different days.