Single-Cell RNA Sequencing Reveals That Adaptation of Human Aortic Endothelial Cells to Antiproliferative Therapies Is Modulated by Flow-Induced Shear Stress

BACKGROUND: Endothelial cells (ECs) are capable of quickly responding in a coordinated manner to a wide array of stresses to maintain vascular homeostasis. Loss of EC cellular adaptation may be a potential marker for cardiovascular disease and a predictor of poor response to endovascular pharmacolog...

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Detalles Bibliográficos
Autores principales: Salazar-Martín, Antonio G., Kalluri, Aditya S., Villanueva, Martin A., Hughes, Travis K., Wadsworth, Marc H., Dao, Tyler T., Balcells, Mercedes, Nezami, Farhad R., Shalek, Alex K., Edelman, Elazer R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Basic Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659257/
https://www.ncbi.nlm.nih.gov/pubmed/37732484
http://dx.doi.org/10.1161/ATVBAHA.123.319283

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