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Glutamate inputs send prediction error of reward but not negative value of aversive stimuli to dopamine neurons

Midbrain dopamine neurons are thought to signal reward prediction errors (RPEs) but the mechanisms underlying RPE computation, particularly contributions of different neurotransmitters, remain poorly understood. Here we used a genetically-encoded glutamate sensor to examine the pattern of glutamate...

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Detalles Bibliográficos
Autores principales: Amo, Ryunosuke, Uchida, Naoshige, Watabe-Uchida, Mitsuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659341/
https://www.ncbi.nlm.nih.gov/pubmed/37986868
http://dx.doi.org/10.1101/2023.11.09.566472