c-Jun Signaling During Initial HSV-1 Infection Modulates Latency to Enhance Later Reactivation in addition to Directly Promoting the Progression to Full Reactivation

Herpes simplex virus-1 (HSV-1) establishes a latent infection in peripheral neurons and can periodically reactivate to permit transmission and clinical manifestations. Viral transactivators required for lytic infection are largely absent during latent infection and therefore HSV-1 relies on the co-o...

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Detalles Bibliográficos
Autores principales: Dochnal, Sara A., Whitford, Abigail L., Francois, Alison K., Krakowiak, Patryk A., Cuddy, Sean, Cliffe, Anna R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659354/
https://www.ncbi.nlm.nih.gov/pubmed/37986840
http://dx.doi.org/10.1101/2023.11.10.566462

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