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Design of a symmetry-broken tetrahedral protein cage by a method of internal steric occlusion

Methods in protein design have made it possible to create large and complex, self-assembling protein cages with diverse applications. These have largely been based on highly symmetric forms exemplified by the Platonic solids. Prospective applications of protein cages would be expanded by strategies...

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Detalles Bibliográficos
Autores principales: Gladkov, Nika, Scott, Elena A., Meador, Kyle, Lee, Eric J., Laganowsky, Arthur D., Yeates, Todd O., Castells-Graells, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659388/
https://www.ncbi.nlm.nih.gov/pubmed/37986890
http://dx.doi.org/10.1101/2023.11.08.566319