Coordinated immune dysregulation in Juvenile Dermatomyositis revealed by single-cell genomics

Juvenile Dermatomyositis (JDM) is one of several childhood-onset autoimmune disorders characterized by a type I interferon response and autoantibodies. Treatment options are limited due to incomplete understanding of how the disease emerges from dysregulated cell states across the immune system. We...

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Detalles Bibliográficos
Autores principales: Rabadam, Gabrielle, Wibrand, Camilla, Flynn, Emily, Hartoularos, George C., Sun, Yang, Ye, Chun Jimmie, Kim, Susan, Gartner, Zev, Sirota, Marina, Neely, Jessica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659396/
https://www.ncbi.nlm.nih.gov/pubmed/37986917
http://dx.doi.org/10.1101/2023.11.07.566033

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