Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes

Proteins containing both intrinsically disordered regions (IDRs) and RNA binding domains (RBDs) can phase separate in vitro, forming bodies similar to cellular biomolecular condensates. However, how IDR and RBD domains contribute to in vivo recruitment of proteins to biomolecular condensates remains...

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Detalles Bibliográficos
Autores principales: O’Connell, Liam C., Johnson, Victoria, Hutton, Anika K., Otis, Jessica P., Murthy, Anastasia C., Liang, Mark C., Wang, Szu-Huan, Fawzi, Nicolas L., Mowry, Kimberly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659413/
https://www.ncbi.nlm.nih.gov/pubmed/37986933
http://dx.doi.org/10.1101/2023.11.10.566489

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