Cargando…

eIF3 engages with 3’-UTR termini of highly translated mRNAs in neural progenitor cells

Stem cell differentiation involves a global increase in protein synthesis to meet the demands of specialized cell types. However, the molecular mechanisms underlying this translational burst and the involvement of initiation factors remains largely unknown. Here, we investigate the roles of eukaryot...

Descripción completa

Detalles Bibliográficos
Autores principales: Mestre-Fos, Santi, Ferguson, Lucas, Trinidad, Marena, Ingolia, Nicholas T., Cate, Jamie H. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659435/
https://www.ncbi.nlm.nih.gov/pubmed/37986910
http://dx.doi.org/10.1101/2023.11.11.566681