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MSGene: Derivation and validation of a multistate model for lifetime risk of coronary artery disease using genetic risk and the electronic health record
Currently, coronary artery disease (CAD) is the leading cause of death among adults worldwide. Accurate risk stratification can support optimal lifetime prevention. We designed a novel and general multistate model (MSGene) to estimate age-specific transitions across 10 cardiometabolic states, depend...
Autores principales: | Urbut, Sarah M., Yeung, Ming Wai, Khurshid, Shaan, Cho, So Mi Jemma, Schuermans, Art, German, Jakob, Taraszka, Kodi, Fahed, Akl C., Ellinor, Patrick, Trinquart, Ludovic, Parmigiani, Giovanni, Gusev, Alexander, Natarajan, Pradeep |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659503/ https://www.ncbi.nlm.nih.gov/pubmed/37986972 http://dx.doi.org/10.1101/2023.11.08.23298229 |
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