Cargando…

Allosteric Neutralization by Human H7N9 Antibodies

The avian influenza A virus H7N9 causes severe human infections with more than 30% fatality despite the use of neuraminidase inhibitors. Currently there is no H7N9-specific prevention or treatment for humans. From a 2013 H7N9 convalescent case occurred in Hong Kong, we isolated four H7 hemagglutinin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jia, Manxue, Zhao, Hanjun, Morano, Nicholas C., Lu, Hong, Lui, Yin-Ming, Du, Haijuan, Becker, Jordan E., Yuen, Kwok-Yung, Ho, David D., Kwong, Peter D., Shapiro, Lawrence, To, Kelvin Kai-Wang, Wu, Xueling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659534/ https://www.ncbi.nlm.nih.gov/pubmed/37986867 http://dx.doi.org/10.21203/rs.3.rs-3429355/v1

Ejemplares similares

SMRT sequencing revealed the diversity and characteristics of defective interfering RNAs in influenza A (H7N9) virus infection
por: Lui, Wing-Yu, et al.
Publicado: (2019)

Gp120 V5 Is Targeted by the First Wave of Sequential Neutralizing Antibodies in SHIV(SF162P3N)-Infected Rhesus Macaques
por: Jia, Manxue, et al.
Publicado: (2018)

An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses
por: Liu, Lihong, et al.
Publicado: (2022)

VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA
por: Jia, Manxue, et al.
Publicado: (2020)

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses
por: Wang, Pengfei, et al.
Publicado: (2021)

A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses
por: Wang, Pengfei, et al.
Publicado: (2021)

Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2
por: Luo, Mengxiao, et al.
Publicado: (2023)

Virus-Like Particle Based Vaccines Elicit Neutralizing Antibodies against the HIV-1 Fusion Peptide
por: Mogus, Alemu Tekewe, et al.
Publicado: (2020)

Somatic Populations of PGT135–137 HIV-1-Neutralizing Antibodies Identified by 454 Pyrosequencing and Bioinformatics
por: Zhu, Jiang, et al.
Publicado: (2012)

Effects of Darwinian Selection and Mutability on Rate of Broadly Neutralizing Antibody Evolution during HIV-1 Infection
por: Sheng, Zizhang, et al.
Publicado: (2016)

Increased resistance of SARS-CoV-2 variant P.1 to antibody neutralization
por: Wang, Pengfei, et al.
Publicado: (2021)

Increased Resistance of SARS-CoV-2 Variant P.1 to Antibody Neutralization
por: Wang, Pengfei, et al.
Publicado: (2021)

High neutralizing antibody titer in intensive care unit patients with COVID-19
por: Liu, Li, et al.
Publicado: (2020)

The emergence of influenza A H7N9 in human beings 16 years after influenza A H5N1: a tale of two cities
por: To, Kelvin KW, et al.
Publicado: (2013)

Performance of a Surrogate SARS-CoV-2-Neutralizing Antibody Assay in Natural Infection and Vaccination Samples
por: Chan, Kwok-Hung, et al.
Publicado: (2021)

Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine
por: Chen, Lin-Lei, et al.
Publicado: (2022)

Cross-reactive antibodies in convalescent SARS patients' sera against the emerging novel human coronavirus EMC (2012) by both immunofluorescent and neutralizing antibody tests
por: Chan, Kwok-Hung, et al.
Publicado: (2013)

A nasal omicron vaccine booster elicits potent neutralizing antibody response against emerging SARS-CoV-2 variants
por: Lam, Joy-Yan, et al.
Publicado: (2022)

Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain
por: Cerutti, Gabriele, et al.
Publicado: (2021)

cAb-Rep: A Database of Curated Antibody Repertoires for Exploring Antibody Diversity and Predicting Antibody Prevalence
por: Guo, Yicheng, et al.
Publicado: (2019)

Generation of neutralizing and non-neutralizing monoclonal antibodies against H7N9 influenza virus
por: Yang, Fan, et al.
Publicado: (2020)

Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies
por: Cerutti, Gabriele, et al.
Publicado: (2021)

In memory of Patrick Manson, founding father of tropical medicine and the discovery of vector-borne infections
por: To, Kelvin KW, et al.
Publicado: (2012)

Increased Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7 to Antibody Neutralization
por: Wang, Pengfei, et al.
Publicado: (2021)

Extended antibody-framework-to-antigen distance observed exclusively with broad HIV-1-neutralizing antibodies recognizing glycan-dense surfaces
por: Lee, Myungjin, et al.
Publicado: (2021)

Broadly neutralizing monoclonal antibodies for HIV prevention
por: Miner, Maurine D., et al.
Publicado: (2021)

Early Pro-Inflammatory Signal and T-Cell Activation Associate With Vaccine-Induced Anti-Vaccinia Protective Neutralizing Antibodies
por: Hou, Jue, et al.
Publicado: (2021)

Seroprevalence of SARS-CoV-2 in Hong Kong returnees – Authors' reply
por: To, Kelvin Kai-Wang, et al.
Publicado: (2020)

Developmental Pathway of the MPER-Directed HIV-1-Neutralizing Antibody 10E8
por: Soto, Cinque, et al.
Publicado: (2016)

Broad-spectrum humanized monoclonal neutralizing antibody against SARS-CoV-2 variants, including the Omicron variant
por: Wen, Kun, et al.
Publicado: (2023)

Paired heavy- and light-chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses
por: Banach, Bailey B., et al.
Publicado: (2021)

Unique reassortant of influenza A(H7N9) virus associated with severe disease emerging in Hong Kong
por: To, Kelvin Kai-Wang, et al.
Publicado: (2014)

Intra-host non-synonymous diversity at a neutralizing antibody epitope of SARS-CoV-2 spike protein N-terminal domain
por: Ip, Jonathan Daniel, et al.
Publicado: (2021)

Human H7N9 virus induces a more pronounced pro-inflammatory cytokine but an attenuated interferon response in human bronchial epithelial cells when compared with an epidemiologically-linked chicken H7N9 virus
por: To, Kelvin K. W., et al.
Publicado: (2016)

Robust SARS-CoV-2 infection in nasal turbinates after treatment with systemic neutralizing antibodies
por: Zhou, Dongyan, et al.
Publicado: (2021)

A broadly neutralizing antibody protects Syrian hamsters against SARS-CoV-2 Omicron challenge
por: Zhou, Biao, et al.
Publicado: (2022)

A broad-spectrum virus- and host-targeting peptide against respiratory viruses including influenza virus and SARS-CoV-2
por: Zhao, Hanjun, et al.
Publicado: (2020)

Free Energy Perturbation Calculation of Relative Binding Free Energy between Broadly Neutralizing Antibodies and the gp120 Glycoprotein of HIV-1
por: Clark, Anthony J., et al.
Publicado: (2017)

Interferon-gamma inhibits influenza A virus cellular attachment by reducing sialic acid cluster size
por: Fong, Carol Ho-Yan, et al.
Publicado: (2022)

Peptidic defective interfering gene nanoparticles against Omicron, Delta SARS-CoV-2 variants and influenza A virus in vivo
por: Zhao, Hanjun, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_gm9k24mobg53vsb17nieatqc90