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Sequence-ensemble-function relationships for disordered proteins in live cells

Intrinsically disordered protein regions (IDRs) are ubiquitous across all kingdoms of life and play a variety of essential cellular roles. IDRs exist in a collection of structurally distinct conformers known as an ensemble. IDR amino acid sequence determines its ensemble, which in turn can play an i...

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Detalles Bibliográficos
Autores principales: Holehouse, Alex, Emenecker, Ryan, Guadalupe, Karina, Shamoon, Nora, Sukenik, Shahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659550/
https://www.ncbi.nlm.nih.gov/pubmed/37986812
http://dx.doi.org/10.21203/rs.3.rs-3501110/v1