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Mutation order in acute myeloid leukemia identifies uncommon patterns of evolution and illuminates phenotypic heterogeneity

Acute myeloid leukemia (AML) has a poor prognosis and a heterogeneous mutation landscape. Although common mutations are well-studied, little research has characterized how the sequence of mutations relates to clinical features. Using published, single-cell DNA sequencing data from three institutions...

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Detalles Bibliográficos
Autores principales:	Majeti, Ravi, Schwede, Matthew, Jahn, Katharina, Kuipers, Jack, Miles, Linde, Bowman, Robert, Robinson, Troy, Furudate, Ken, Uryu, Hidetaka, Tanaka, Tomoyuki, Sasaki, Yuya, Ediriwickrema, Asiri, Benard, Brooks, Gentles, Andrew, Levine, Ross, Beerenwinkel, Niko, Takahashi, Koichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Journal Experts 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659552/ https://www.ncbi.nlm.nih.gov/pubmed/37986825 http://dx.doi.org/10.21203/rs.3.rs-3516536/v1

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