Adipose-derived exosomal miR-421 targets CBX7 and promotes metastatic potential in ovarian cancer cells

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BACKGROUND: Chromobox protein homolog 7 (CBX7), a member of the Polycomb repressor complex, is a potent epigenetic regulator and gene silencer. Our group has previously reported that CBX7 functions as a tumor suppressor in ovarian cancer cells and its loss accelerated formation of carcinomatosis and...

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Detalles Bibliográficos
Autores principales: Zhang, Yi, Tedja, Roslyn, Millman, Michael, Wong, Terrence, Fox, Alexandra, Chehade, Hussein, Gershater, Meyer, Adzibolosu, Nicholas, Gogoi, Radhika, Anderson, Matthew, Rutherford, Thomas, Zhang, Zhenggang, Chopp, Michael, Mor, Gil, Alvero, Ayesha B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659572/
https://www.ncbi.nlm.nih.gov/pubmed/37986971
http://dx.doi.org/10.1101/2023.11.07.566022
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