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Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report

RATIONALE: Perianal abscess is a common disease of the anus and intestine. Surgery is an important treatment option for perianal abscess. However, some patients have a long healing time, poor healing effect after surgery, or even pseudo-healing. Platelet-rich plasma (PRP) is rich in platelets that c...

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Autores principales: Liang, Shuang, Ma, Weijuan, Jia, Sihui, Zhao, Gang, Li, Ying, Li, Yaxin, Wang, Licun, Liu, Zheng, Liu, Jiao, Gao, Hairui, Wang, Haiyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659616/
https://www.ncbi.nlm.nih.gov/pubmed/37986293
http://dx.doi.org/10.1097/MD.0000000000035996
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author Liang, Shuang
Ma, Weijuan
Jia, Sihui
Zhao, Gang
Li, Ying
Li, Yaxin
Wang, Licun
Liu, Zheng
Liu, Jiao
Gao, Hairui
Wang, Haiyan
author_facet Liang, Shuang
Ma, Weijuan
Jia, Sihui
Zhao, Gang
Li, Ying
Li, Yaxin
Wang, Licun
Liu, Zheng
Liu, Jiao
Gao, Hairui
Wang, Haiyan
author_sort Liang, Shuang
collection PubMed
description RATIONALE: Perianal abscess is a common disease of the anus and intestine. Surgery is an important treatment option for perianal abscess. However, some patients have a long healing time, poor healing effect after surgery, or even pseudo-healing. Platelet-rich plasma (PRP) is rich in platelets that can release a large number of factors when activated and promote wound healing. Moreover, there are few reports on the use of PRP for wounds that are difficult to heal after perianal abscess surgery. PATIENT CONCERNS: The patient had reported a complaint of perianal swelling and discomfort associated with anal pain, which was considered a perianal abscess. Ceftriaxone, fumigation, and sitz bath were administered after mixed hemorrhoid and perianal abscess surgeries were performed; however, the wound remained unhealed for more than 3 months, and there was a fistula under the skin. DIAGNOSIS: Perianal color ultrasonography revealed perianal abscess. INTERVENTIONS: Autologous PRP treatment was performed 5 times for each patient. OUTCOMES: The postoperative wound healed within 15 days after 5 times PRP treatments. LESSONS: PRP is a novel treatment option for pseudo-healing.
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spelling pubmed-106596162023-11-17 Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report Liang, Shuang Ma, Weijuan Jia, Sihui Zhao, Gang Li, Ying Li, Yaxin Wang, Licun Liu, Zheng Liu, Jiao Gao, Hairui Wang, Haiyan Medicine (Baltimore) 4500 RATIONALE: Perianal abscess is a common disease of the anus and intestine. Surgery is an important treatment option for perianal abscess. However, some patients have a long healing time, poor healing effect after surgery, or even pseudo-healing. Platelet-rich plasma (PRP) is rich in platelets that can release a large number of factors when activated and promote wound healing. Moreover, there are few reports on the use of PRP for wounds that are difficult to heal after perianal abscess surgery. PATIENT CONCERNS: The patient had reported a complaint of perianal swelling and discomfort associated with anal pain, which was considered a perianal abscess. Ceftriaxone, fumigation, and sitz bath were administered after mixed hemorrhoid and perianal abscess surgeries were performed; however, the wound remained unhealed for more than 3 months, and there was a fistula under the skin. DIAGNOSIS: Perianal color ultrasonography revealed perianal abscess. INTERVENTIONS: Autologous PRP treatment was performed 5 times for each patient. OUTCOMES: The postoperative wound healed within 15 days after 5 times PRP treatments. LESSONS: PRP is a novel treatment option for pseudo-healing. Lippincott Williams & Wilkins 2023-11-17 /pmc/articles/PMC10659616/ /pubmed/37986293 http://dx.doi.org/10.1097/MD.0000000000035996 Text en Copyright © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle 4500
Liang, Shuang
Ma, Weijuan
Jia, Sihui
Zhao, Gang
Li, Ying
Li, Yaxin
Wang, Licun
Liu, Zheng
Liu, Jiao
Gao, Hairui
Wang, Haiyan
Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title_full Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title_fullStr Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title_full_unstemmed Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title_short Application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: A case report
title_sort application of platelet-rich-plasma in the postoperative treatment of perianal abscess pseudohealing: a case report
topic 4500
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659616/
https://www.ncbi.nlm.nih.gov/pubmed/37986293
http://dx.doi.org/10.1097/MD.0000000000035996
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