Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report

Fanconi anemia (FA) is a very rare form of aplastic anemia. Patients with FA have a higher risk of developing solid tumors such as head and neck squamous cell carcinoma, higher risk of local recurrence, and impaired resistance to chemotherapy and radiotherapy treatments than the normal population. I...

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Autores principales: Gargiulo, Maurizio, Petroccione, Carlo, Razzano, Sergio, La Torre, Francesca, Manfellotto, Vincenzo, D’Aniello, Giuseppe, Barbieri, Gerarda, d’Alessio, Matteo, Nicoletti, Giovanni Francesco, Ferraro, Giuseppe Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Reconstructive
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659727/
https://www.ncbi.nlm.nih.gov/pubmed/38025634
http://dx.doi.org/10.1097/GOX.0000000000005414
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author Gargiulo, Maurizio
Petroccione, Carlo
Razzano, Sergio
La Torre, Francesca
Manfellotto, Vincenzo
D’Aniello, Giuseppe
Barbieri, Gerarda
d’Alessio, Matteo
Nicoletti, Giovanni Francesco
Ferraro, Giuseppe Andrea
author_facet Gargiulo, Maurizio
Petroccione, Carlo
Razzano, Sergio
La Torre, Francesca
Manfellotto, Vincenzo
D’Aniello, Giuseppe
Barbieri, Gerarda
d’Alessio, Matteo
Nicoletti, Giovanni Francesco
Ferraro, Giuseppe Andrea
author_sort Gargiulo, Maurizio
collection PubMed
description Fanconi anemia (FA) is a very rare form of aplastic anemia. Patients with FA have a higher risk of developing solid tumors such as head and neck squamous cell carcinoma, higher risk of local recurrence, and impaired resistance to chemotherapy and radiotherapy treatments than the normal population. In this article, we describe the challenging clinical case of a patient with FA who underwent surgery for the removal of a large squamous cell carcinoma in the oral cavity. Mandibular reconstruction was performed using a biaxial double-barrel fibular flap, with excellent functional aesthetic outcomes.
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spelling pubmed-106597272023-11-20 Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report Gargiulo, Maurizio Petroccione, Carlo Razzano, Sergio La Torre, Francesca Manfellotto, Vincenzo D’Aniello, Giuseppe Barbieri, Gerarda d’Alessio, Matteo Nicoletti, Giovanni Francesco Ferraro, Giuseppe Andrea Plast Reconstr Surg Glob Open Reconstructive Fanconi anemia (FA) is a very rare form of aplastic anemia. Patients with FA have a higher risk of developing solid tumors such as head and neck squamous cell carcinoma, higher risk of local recurrence, and impaired resistance to chemotherapy and radiotherapy treatments than the normal population. In this article, we describe the challenging clinical case of a patient with FA who underwent surgery for the removal of a large squamous cell carcinoma in the oral cavity. Mandibular reconstruction was performed using a biaxial double-barrel fibular flap, with excellent functional aesthetic outcomes. Lippincott Williams & Wilkins 2023-11-20 /pmc/articles/PMC10659727/ /pubmed/38025634 http://dx.doi.org/10.1097/GOX.0000000000005414 Text en Copyright © 2023 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Reconstructive
Gargiulo, Maurizio
Petroccione, Carlo
Razzano, Sergio
La Torre, Francesca
Manfellotto, Vincenzo
D’Aniello, Giuseppe
Barbieri, Gerarda
d’Alessio, Matteo
Nicoletti, Giovanni Francesco
Ferraro, Giuseppe Andrea
Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title_full Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title_fullStr Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title_full_unstemmed Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title_short Squamous Carcinoma of the Oral Cavity in Patient with Fanconi Anemia: A Challenging Reconstruction with Double-barrel Free Fibula Flap Case Report
title_sort squamous carcinoma of the oral cavity in patient with fanconi anemia: a challenging reconstruction with double-barrel free fibula flap case report
topic Reconstructive
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659727/
https://www.ncbi.nlm.nih.gov/pubmed/38025634
http://dx.doi.org/10.1097/GOX.0000000000005414
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