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Effects of pharmacogenetic profiles on pediatric pain relief and adverse events with ibuprofen and oxycodone

INTRODUCTION: Individual genetic variation may influence clinical effects for pain medications. Effects of CYP2C9, CYP3A4, and CYP2D6 polymorphisms on clinical effectiveness and safety for ibuprofen and oxycodone were studied. OBJECTIVE: Primary objectives were to AU2 evaluate if allelic variations...

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Detalles Bibliográficos
Autores principales: Ali, Samina, Yukseloglu, Aran, Ross, Colin J., Rosychuk, Rhonda J., Drendel, Amy L., Manaloor, Robin, Johnson, David W., Le May, Sylvie, Carleton, Bruce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659733/
https://www.ncbi.nlm.nih.gov/pubmed/38027465
http://dx.doi.org/10.1097/PR9.0000000000001113