H. pylori‐induced NF‐κB‐PIEZO1‐YAP1‐CTGF axis drives gastric cancer progression and cancer‐associated fibroblast‐mediated tumour microenvironment remodelling

BACKGROUND: Gastric cancer (GC) is one of the most common tumours in East Asia countries and is associated with Helicobacter pylori infection. H. pylori utilizes virulence factors, CagA and VacA, to up‐regulate pro‐inflammatory cytokines and activate NF‐κB signaling. Meanwhile, the PIEZO1 upregulati...

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Detalles Bibliográficos
Autores principales: Chen, Bonan, Liu, Xiaoli, Yu, Peiyao, Xie, Fuda, Kwan, Johnny S. H., Chan, Wai Nok, Fang, Canbin, Zhang, Jinglin, Cheung, Alvin H. K., Chow, Chit, Leung, Gloria W. M., Leung, Kam Tong, Shi, Shihua, Zhang, Bin, Wang, Shouyu, Xu, Dazhi, Fu, Kaili, Wong, Chi Chun, Wu, William K. K., Chan, Michael W. Y., Tang, Patrick M. K., Tsang, Chi Man, Lo, Kwok Wai, Tse, Gary M. K., Yu, Jun, To, Ka Fai, Kang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659770/
https://www.ncbi.nlm.nih.gov/pubmed/37983931
http://dx.doi.org/10.1002/ctm2.1481

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