Multimodal, broadly neutralizing antibodies against SARS-CoV-2 identified by high-throughput native pairing of BCRs from bulk B cells

TruAB Discovery is an approach that integrates cellular immunology, high-throughput immunosequencing, bioinformatics, and computational biology in order to discover naturally occurring human antibodies for prophylactic or therapeutic use. We adapted our previously described pairSEQ technology to pai...

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Detalles Bibliográficos
Autores principales: Keitany, Gladys J., Rubin, Benjamin E.R., Garrett, Meghan E., Musa, Andrea, Tracy, Jeff, Liang, Yu, Ebert, Peter, Moore, Amanda J., Guan, Jonathan, Eggers, Erica, Lescano, Ninnia, Brown, Ryan, Carbo, Adria, Al-Asadi, Hussein, Ching, Travers, Day, Austin, Harris, Rebecca, Linkem, Charles, Popov, Dimitry, Wilkins, Courtney, Li, Lianqu, Wang, Jiao, Liu, Chuanxin, Chen, Li, Dines, Jennifer N., Atyeo, Caroline, Alter, Galit, Baldo, Lance, Sherwood, Anna, Howie, Bryan, Klinger, Mark, Yusko, Erik, Robins, Harlan S., Benzeno, Sharon, Gilbert, Amy E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10659930/
https://www.ncbi.nlm.nih.gov/pubmed/37586370
http://dx.doi.org/10.1016/j.chembiol.2023.07.011

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