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von Willebrand factor modulates immune complexes and the recall response against factor VIII in a murine hemophilia A model

Achieving tolerance toward factor VIII (FVIII) remains an important goal of hemophilia treatment. Up to 40% of patients with severe hemophilia A (HA) develop neutralizing antibodies against FVIII, and the only proven treatment to achieve tolerance is infusion of FVIII over prolonged periods in the c...

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Detalles Bibliográficos
Autores principales:	Oleshko, Olga, Vollack-Hesse, Nadine, Tiede, Andreas, Hegermann, Jan, Curth, Ute, Werwitzke, Sonja
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society of Hematology 2023
Materias:	Thrombosis and Hemostasis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660012/ https://www.ncbi.nlm.nih.gov/pubmed/37756521 http://dx.doi.org/10.1182/bloodadvances.2023010388

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