Cargando…

Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt

INTRODUCTION: Suicide behaviour is a complex and multifactor concept that includes different risk factors. According with literature a dimensional concept of illness could help to understand this complexity and clarify clinical aspects of suicide risk. OBJECTIVES: The aim of this study is to identif...

Descripción completa

Detalles Bibliográficos
Autores principales: Saiz-Gonzalez, D., Diaz-Carracedo, P., Pemau, A., Ayad-Ahmed, W., Veronica, F.-R., Navas Tejedor, M., de la Torre-Luque, A., Diaz-Marsa, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660072/
http://dx.doi.org/10.1192/j.eurpsy.2023.1181
_version_ 1785137684169097216
author Saiz-Gonzalez, D.
Diaz-Carracedo, P.
Pemau, A.
Ayad-Ahmed, W.
Veronica, F.-R.
Navas Tejedor, M.
de la Torre-Luque, A.
Diaz-Marsa, M.
author_facet Saiz-Gonzalez, D.
Diaz-Carracedo, P.
Pemau, A.
Ayad-Ahmed, W.
Veronica, F.-R.
Navas Tejedor, M.
de la Torre-Luque, A.
Diaz-Marsa, M.
author_sort Saiz-Gonzalez, D.
collection PubMed
description INTRODUCTION: Suicide behaviour is a complex and multifactor concept that includes different risk factors. According with literature a dimensional concept of illness could help to understand this complexity and clarify clinical aspects of suicide risk. OBJECTIVES: The aim of this study is to identify different profiles of symptoms in a sample of suicide attempters and the relationship between this profiles and suicide behaviour in terms of outcome: presence and intensity of suicidal ideation, presence and number of attempts and severity of the medical damage in the current attempt. METHODS: 634 patients were recruited at the psychiatry emergency of eight public general hospitals in Spain between November 2020 until February 2022 in the SURVIVE protocol. The patients were assessed in 15 days using a battery of clinical tools that includes Brief Symptom Inventory, a sociodemographic interview, Mini Clinical Interview and C-SSRS, ACSS and BIS-11 scales. Latent profile analysis was applied to obtain profile symptoms. Logistic and multivariant regression was used to obtain data about outcome. RESULTS: Three clinical profiles of psychiatric symptoms were described in suicide attempters (p < 0.01): high symptoms (HS) (45.02%), moderate symptoms (MS) (42.5 %) and low symptoms (LS) (12.48%). Significant differences were found between classes in four symptom domains (Figure 1): anxiety, obsessive-compulsive, sensitivity, and somatization (p < 0.01). Participants of the HS class showed higher values in relation with the BSI summary indexes, and more diagnoses, higher levels of suicidal ideation and suicidal related behaviour as well as higher acquired capability for suicide. Participants of the LS class were more likely to be women, older and unemployed and was related, according the analysis, with severe medical damage when compared with other groups (P< 0.01). Image: CONCLUSIONS: According with the predictive model the study suggests different symptom-frequency clusters related with suicide attempt outcomes. Suicide ideation presence and intensity is related with HS class and acquired capability of suicide. Suicide ideation intensity is also related with number of diagnosis and number of previous attempts. Suicide behaviours presence is associated with being student and number with HS profile. Both presence and number were related with number of diagnosis as well as number of previous attempts (the higher all these clinical factors, the more intense of ideation in the last month). Finally, the severity of medical damage was related with LS profile and unemployed/retired work status. The dimensional symptom profile could be useful to predict suicide attempt outcome. Further study is needed to clarify this relation. DISCLOSURE OF INTEREST: None Declared
format Online
Article
Text
id pubmed-10660072
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cambridge University Press
record_format MEDLINE/PubMed
spelling pubmed-106600722023-07-19 Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt Saiz-Gonzalez, D. Diaz-Carracedo, P. Pemau, A. Ayad-Ahmed, W. Veronica, F.-R. Navas Tejedor, M. de la Torre-Luque, A. Diaz-Marsa, M. Eur Psychiatry Abstract INTRODUCTION: Suicide behaviour is a complex and multifactor concept that includes different risk factors. According with literature a dimensional concept of illness could help to understand this complexity and clarify clinical aspects of suicide risk. OBJECTIVES: The aim of this study is to identify different profiles of symptoms in a sample of suicide attempters and the relationship between this profiles and suicide behaviour in terms of outcome: presence and intensity of suicidal ideation, presence and number of attempts and severity of the medical damage in the current attempt. METHODS: 634 patients were recruited at the psychiatry emergency of eight public general hospitals in Spain between November 2020 until February 2022 in the SURVIVE protocol. The patients were assessed in 15 days using a battery of clinical tools that includes Brief Symptom Inventory, a sociodemographic interview, Mini Clinical Interview and C-SSRS, ACSS and BIS-11 scales. Latent profile analysis was applied to obtain profile symptoms. Logistic and multivariant regression was used to obtain data about outcome. RESULTS: Three clinical profiles of psychiatric symptoms were described in suicide attempters (p < 0.01): high symptoms (HS) (45.02%), moderate symptoms (MS) (42.5 %) and low symptoms (LS) (12.48%). Significant differences were found between classes in four symptom domains (Figure 1): anxiety, obsessive-compulsive, sensitivity, and somatization (p < 0.01). Participants of the HS class showed higher values in relation with the BSI summary indexes, and more diagnoses, higher levels of suicidal ideation and suicidal related behaviour as well as higher acquired capability for suicide. Participants of the LS class were more likely to be women, older and unemployed and was related, according the analysis, with severe medical damage when compared with other groups (P< 0.01). Image: CONCLUSIONS: According with the predictive model the study suggests different symptom-frequency clusters related with suicide attempt outcomes. Suicide ideation presence and intensity is related with HS class and acquired capability of suicide. Suicide ideation intensity is also related with number of diagnosis and number of previous attempts. Suicide behaviours presence is associated with being student and number with HS profile. Both presence and number were related with number of diagnosis as well as number of previous attempts (the higher all these clinical factors, the more intense of ideation in the last month). Finally, the severity of medical damage was related with LS profile and unemployed/retired work status. The dimensional symptom profile could be useful to predict suicide attempt outcome. Further study is needed to clarify this relation. DISCLOSURE OF INTEREST: None Declared Cambridge University Press 2023-07-19 /pmc/articles/PMC10660072/ http://dx.doi.org/10.1192/j.eurpsy.2023.1181 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Saiz-Gonzalez, D.
Diaz-Carracedo, P.
Pemau, A.
Ayad-Ahmed, W.
Veronica, F.-R.
Navas Tejedor, M.
de la Torre-Luque, A.
Diaz-Marsa, M.
Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title_full Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title_fullStr Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title_full_unstemmed Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title_short Psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
title_sort psychopathological symptoms as clinical phenotypes in suicide attempters: relation in terms of suicidal ideation, suicidal related behaviors and medical damage of the attempt
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660072/
http://dx.doi.org/10.1192/j.eurpsy.2023.1181
work_keys_str_mv AT saizgonzalezd psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT diazcarracedop psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT pemaua psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT ayadahmedw psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT veronicafr psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT navastejedorm psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT delatorreluquea psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt
AT diazmarsam psychopathologicalsymptomsasclinicalphenotypesinsuicideattemptersrelationintermsofsuicidalideationsuicidalrelatedbehaviorsandmedicaldamageoftheattempt