Cargando…

Scientific techniques in adolescent and young adult classic Hodgkin lymphoma

Understanding the tumor microenvironment and genomic landscape is crucial for better prediction of treatment outcomes and developing novel therapies in Hodgkin lymphoma (HL). Recent advancements in genomics have enabled researchers to gain deeper insights into the genomic characteristics of HL at bo...

Descripción completa

Detalles Bibliográficos
Autores principales: Maura, Francesco, Adams, Ragini M., Aoki, Tomohiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660113/
https://www.ncbi.nlm.nih.gov/pubmed/38024640
http://dx.doi.org/10.1002/jha2.786
Descripción
Sumario:Understanding the tumor microenvironment and genomic landscape is crucial for better prediction of treatment outcomes and developing novel therapies in Hodgkin lymphoma (HL). Recent advancements in genomics have enabled researchers to gain deeper insights into the genomic characteristics of HL at both single‐cell resolution and the whole genome level. The use of noninvasive methods such as liquid biopsies and formalin‐fixed paraffin‐embedded‐based imaging techniques has expanded the possibilities of applying cutting‐edge analyses to routine clinically available samples. Collaborative efforts between adult and pediatric group are imperative to translate novel findings into routine patient care.