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A combined crystallographic and theoretical investigation of noncovalent interactions in 1,3,4-oxadiazole-2-thione-N-Mannich derivatives: in vitro bioactivity and molecular docking

Two 1,3,4-oxadiazole-2-thione-N-Mannich derivatives, specifically 5-(4-chlorophenyl)-3-[(2-trifluoromethylphenylamino)methyl]-1,3,4-oxadiazole-2(3H)-thione (1) and 5-(4-chlorophenyl)-3-[(2,5-difluorophenylamino)methyl]-1,3,4-oxadiazole-2(3H)-thione (2), were synthesized and then characterized by ele...

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Detalles Bibliográficos
Autores principales:	Al-Wahaibi, Lamya H., Alagappan, Kowsalya, Gomila, Rosa M., Blacque, Olivier, Frontera, Antonio, Percino, M. Judith, El-Emam, Ali A., Thamotharan, Subbiah
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2023
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660235/ https://www.ncbi.nlm.nih.gov/pubmed/38019986 http://dx.doi.org/10.1039/d3ra07169c

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