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Persistence of UBTF tandem duplications in remission in acute myeloid leukaemia

UBTF tandem duplications are recurrent in adult and paediatric acute myeloid leukaemia and have been reported to be associated with a poor prognosis. Co‐mutations in WT1 and FLT3 are common while morphological dysplasia is frequent. The role of UBTF‐TDs in leukemogenesis is yet to be elucidated; how...

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Detalles Bibliográficos
Autores principales: Harrop, Sean, Nguyen, Phillip C., Byrne, David, Wilson, Clarissa, Ryland, Georgina L., Nguyen, Tamia, Anderson, Mary Ann, Khaw, Seong Lin, Martin, Michelle, Tiong, Ing Soo, Sanij, Elaine, Blombery, Piers
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660390/
https://www.ncbi.nlm.nih.gov/pubmed/38024622
http://dx.doi.org/10.1002/jha2.808