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Evaluation of Two Chemoenzymatic Glycan Remodeling Approaches to Generate Site-Specific Antibody–Drug Conjugates

Fc-glycosite-specific antibody–drug conjugation represents a promising direction for the preparation of site-specific antibody–drug conjugates (ADCs). In the present research, we conducted a systemic evaluation of two endoglycosidase-catalyzed chemoenzymatic glycoengineering technologies to prepare...

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Detalles Bibliográficos
Autores principales:	Yang, Qiang, Chen, He, Ou, Chong, Zheng, Zhihao, Zhang, Xiao, Liu, Yunpeng, Zong, Guanghui, Wang, Lai-Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660516/ https://www.ncbi.nlm.nih.gov/pubmed/37987249 http://dx.doi.org/10.3390/antib12040071

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