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Metabolic reprogramming, autophagy, and ferroptosis: Novel arsenals to overcome immunotherapy resistance in gastrointestinal cancer

BACKGROUND: Gastrointestinal cancer poses a serious health threat owing to its high morbidity and mortality. Although immune checkpoint blockade (ICB) therapies have achieved meaningful success in most solid tumors, the improvement in survival in gastrointestinal cancers is modest, owing to sparse i...

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Detalles Bibliográficos
Autores principales: Wang, Xiangwen, Zhou, Liwen, Wang, Hongpeng, Chen, Wei, Jiang, Lei, Ming, Guangtao, Wang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660574/
https://www.ncbi.nlm.nih.gov/pubmed/37860928
http://dx.doi.org/10.1002/cam4.6623