Cargando…

Inhibitory role of bone marrow mesenchymal stem cells‐derived exosome in non‐small‐cell lung cancer: microRNA‐30b‐5p, EZH2 and PI3K/AKT pathway

Exosomal microRNA (miRNA) exerts potential roles in non‐small‐cell lung cancer (NSCLC). The current study elucidated the role of miR‐30b‐5p shuttled by bone marrow mesenchymal stem cells (BMSCs)‐derived exosomes in treating NSCLC. Bioinformatics analysis was performed with NSCLC‐related miRNA microa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Tong, Tian, Qi, Liu, Ruiji, Xu, Ke, Shi, Shanshan, Zhang, Xiudi, Gao, Liming, Yin, Xiaobo, Xu, Shufeng, Wang, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2023
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660609/ https://www.ncbi.nlm.nih.gov/pubmed/37698037 http://dx.doi.org/10.1111/jcmm.17933

Ejemplares similares

Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts
por: Li, Fang-Qi, et al.
Publicado: (2023)

MicroRNA-138 suppresses cell proliferation in laryngeal squamous cell carcinoma via inhibiting EZH2 and PI3K/AKT signaling
por: Si, Fengzhi, et al.
Publicado: (2017)

MicroRNA-138 suppresses cell proliferation in laryngeal squamous cell carcinoma via inhibiting EZH2 and PI3K/AKT signaling
por: Si, Fengzhi, et al.
Publicado: (2021)

EZH2 mitigates the cardioprotective effects of mesenchymal stem cell-secreted exosomes against infarction via HMGA2-mediated PI3K/AKT signaling
por: Jiao, Wei, et al.
Publicado: (2022)

si-PDGFRβ-Loaded Exosomes Suppress the Progression of Glioma by Inhibiting the Oxidative Associated PI3K/Akt/EZH2 Signaling Pathway
por: Li, Yuping, et al.
Publicado: (2022)

Indirect Tumor Inhibitory Effects of MicroRNA-124 through Targeting EZH2 in The Multiple Myeloma Cell Line
por: Sabour Takanlu, Javid, et al.
Publicado: (2020)

Bone Marrow Mesenchymal Stem Cell-Derived Exosomes Inhibit Triple-Negative Breast Cancer Cell Stemness and Metastasis via an ALKBH5-Dependent Mechanism
por: Hu, Yun, et al.
Publicado: (2022)

Bone marrow mesenchymal stem cell‐derived exosomes reduce insulin resistance and obesity in mice via the PI3K/AKT signaling pathway
por: Shi, Hongwei, et al.
Publicado: (2023)

Circulating myocardial microRNAs from infarcted hearts are carried in exosomes and mobilise bone marrow progenitor cells
por: Cheng, Min, et al.
Publicado: (2019)

M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway
por: Yao, Jie, et al.
Publicado: (2021)

MT1G inhibits the growth and epithelial-mesenchymal transition of gastric cancer cells by regulating the PI3K/AKT signaling pathway
por: Xu, Guofeng, et al.
Publicado: (2022)

Correction to: M2 macrophage-derived exosomal microRNAs inhibit cell migration and invasion in gliomas through PI3K/AKT/mTOR signaling pathway
por: Yao, Jie, et al.
Publicado: (2021)

LINC00665 Induces Acquired Resistance to Gefitinib through Recruiting EZH2 and Activating PI3K/AKT Pathway in NSCLC
por: Liu, Xinyin, et al.
Publicado: (2019)

Mesenchymal stem cell-derived exosomal microRNA-133b suppresses glioma progression via Wnt/β-catenin signaling pathway by targeting EZH2
por: Xu, Haiyang, et al.
Publicado: (2019)

MicroRNAs of bone marrow mesenchymal stem cell-derived exosomes regulate acute myeloid leukemia cell proliferation and apoptosis
por: Xu, Yi-Chuan, et al.
Publicado: (2020)

Bone marrow mesenchymal stem cell-derived exosomal microRNA regulates microglial polarization
por: Huang, Xianwei, et al.
Publicado: (2023)

Functional role of MicroRNA/PI3K/AKT axis in osteosarcoma
por: Xiang, Yubo, et al.
Publicado: (2023)

Thioacetamide promotes osteoclast transformation of bone marrow macrophages by influencing PI3K/AKT pathways
por: Jin, XiaoLi, et al.
Publicado: (2022)

Exosomal circRNA_100284 from arsenite-transformed cells, via microRNA-217 regulation of EZH2, is involved in the malignant transformation of human hepatic cells by accelerating the cell cycle and promoting cell proliferation
por: Dai, Xiangyu, et al.
Publicado: (2018)

Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway
por: Fu, Xiao, et al.
Publicado: (2018)

The Role of KDM2B and EZH2 in Regulating the Stemness in Colorectal Cancer Through the PI3K/AKT Pathway
por: Sanches, Jaceline Gisliane Pires, et al.
Publicado: (2021)

Suppressing MicroRNA-30b by Estrogen Promotes Osteogenesis in Bone Marrow Mesenchymal Stem Cells
por: Liu, Guanqi, et al.
Publicado: (2019)

Dimethyloxaloylglycine-stimulated human bone marrow mesenchymal stem cell-derived exosomes enhance bone regeneration through angiogenesis by targeting the AKT/mTOR pathway
por: Liang, Bo, et al.
Publicado: (2019)

The PI3KCA and AKT Inhibitory Activities of Litsea Cubeba Lour. Fruits and Heartwoods Towards Hela Cells
por: Dalimunthe, Aminah, et al.
Publicado: (2019)

EZH2 Gene Knockdown Inhibits Sheep Pituitary Cell Proliferation via Downregulating the AKT/ERK Signaling Pathway
por: Cai, Yu, et al.
Publicado: (2023)

Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction
por: Zhao, Ende, et al.
Publicado: (2015)

Exosomes Play an Important Role in the Progression of Plasma Cell Mastitis via the PI3K-Akt-mTOR Signaling Pathway
por: Wang, Xiaohong, et al.
Publicado: (2019)

Altered MicroRNA Expression Profile in Exosomes during Osteogenic Differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells
por: Xu, Ji-Feng, et al.
Publicado: (2014)

Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway
por: Zhang, Zeliang, et al.
Publicado: (2023)

DPY30 promotes the growth and survival of osteosarcoma cells by regulating the PI3K/AKT signal pathway
por: Cheng, Gong, et al.
Publicado: (2022)

Bone marrow mesenchymal stem cell-derived exosomal miR-21 protects C-kit(+) cardiac stem cells from oxidative injury through the PTEN/PI3K/Akt axis
por: Shi, Bei, et al.
Publicado: (2018)

Exosomes from PYCR1 knockdown bone marrow mesenchymal stem inhibits aerobic glycolysis and the growth of bladder cancer cells via regulation of the EGFR/PI3K/AKT pathway
por: Li, Zhuo, et al.
Publicado: (2023)

Effects of Platycodin D on Proliferation, Apoptosis and PI3K/Akt Signal Pathway of Human Glioma U251 Cells
por: Xu, Chong, et al.
Publicado: (2014)

Apolipoprotein D alleviates glucocorticoid-induced osteogenesis suppression in bone marrow mesenchymal stem cells via the PI3K/Akt pathway
por: Yu, Rong-Hua, et al.
Publicado: (2020)

microRNA-214 suppresses the growth of cervical cancer cells by targeting EZH2
por: Yang, Yanling, et al.
Publicado: (2018)

Asperosaponin VI promotes bone marrow stromal cell osteogenic differentiation through the PI3K/AKT signaling pathway in an osteoporosis model
por: Ke, Ke, et al.
Publicado: (2016)

Therapeutic effects of bone marrow mesenchymal stem cells‐derived exosomes on osteoarthritis
por: Jin, Yi, et al.
Publicado: (2021)

Exosomes from microRNA‐126 overexpressing mesenchymal stem cells promote angiogenesis by targeting the PIK3R2‐mediated PI3K/Akt signalling pathway
por: Zhang, Lei, et al.
Publicado: (2020)

Retraction Note: Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway
por: Fu, Xiao, et al.
Publicado: (2023)

Suppressive function of bone marrow-derived mesenchymal stem cell-derived exosomal microRNA-187 in prostate cancer
por: Li, Chuangui, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ds9ai91j8742m93l0flh7e17fo