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ROR2 deficit may induce the tetralogy of Fallot via down‐regulating of β‐catenin/SOX3/HSPA6 in vitro and in vivo

Tetralogy of Fallot (TOF) is the highly conventional appearance of cyanotic congenital heart disease. Our study aimed to assess the involvement of receptor tyrosine kinase‐like orphan receptor 2 (ROR2) in TOF and elucidate the specific mechanism. Upon investigation of human tissue samples, we observ...

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Detalles Bibliográficos
Autores principales: Guo, Rui, Guo, Yiran Zhou, Zhou, Qing, Li, Guoju, Du, Zhanghui, Shi, Yefei, Xing, Quansheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10660643/
https://www.ncbi.nlm.nih.gov/pubmed/37749917
http://dx.doi.org/10.1111/jcmm.17969