Maximizing Heterologous Expression of Engineered Type I Polyketide Synthases: Investigating Codon Optimization Strategies

[Image: see text] Type I polyketide synthases (T1PKSs) hold enormous potential as a rational production platform for the biosynthesis of specialty chemicals. However, despite great progress in this field, the heterologous expression of PKSs remains a major challenge. One of the first measures to imp...

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Detalles Bibliográficos
Autores principales: Schmidt, Matthias, Lee, Namil, Zhan, Chunjun, Roberts, Jacob B., Nava, Alberto A., Keiser, Leah S., Vilchez, Aaron A., Chen, Yan, Petzold, Christopher J., Haushalter, Robert W., Blank, Lars M., Keasling, Jay D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661030/
https://www.ncbi.nlm.nih.gov/pubmed/37851920
http://dx.doi.org/10.1021/acssynbio.3c00367

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