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A Rapid Antibody Enhancement Platform in Saccharomyces cerevisiae Using an Improved, Diversifying CRISPR Base Editor

[Image: see text] The yeast Saccharomyces cerevisiae is commonly used to interrogate and screen protein variants and to perform directed evolution studies to develop proteins with enhanced features. While several techniques have been described that help enable the use of yeast for directed evolution...

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Detalles Bibliográficos
Autores principales: Cazier, Andrew P., Irvin, Olivia M., Chávez, Lizmarie S., Dalvi, Saachi, Abraham, Hannah, Wickramanayake, Nevinka, Yellayi, Sreenivas, Blazeck, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661033/
https://www.ncbi.nlm.nih.gov/pubmed/37873982
http://dx.doi.org/10.1021/acssynbio.3c00299