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A Rapid Antibody Enhancement Platform in Saccharomyces cerevisiae Using an Improved, Diversifying CRISPR Base Editor
[Image: see text] The yeast Saccharomyces cerevisiae is commonly used to interrogate and screen protein variants and to perform directed evolution studies to develop proteins with enhanced features. While several techniques have been described that help enable the use of yeast for directed evolution...
Autores principales: | Cazier, Andrew P., Irvin, Olivia M., Chávez, Lizmarie S., Dalvi, Saachi, Abraham, Hannah, Wickramanayake, Nevinka, Yellayi, Sreenivas, Blazeck, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661033/ https://www.ncbi.nlm.nih.gov/pubmed/37873982 http://dx.doi.org/10.1021/acssynbio.3c00299 |
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