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Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants

[Image: see text] The Bxb1 bacteriophage serine DNA recombinase is an efficient tool for engineering recombinant DNA into the genomes of cultured cells. Generally, a single engineered “landing pad” site is introduced into the cell genome, permitting the integration of transgenic circuits or librarie...

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Detalles Bibliográficos
Autores principales: Roelle, Sarah M., Kamath, Nisha D., Matreyek, Kenneth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661055/
https://www.ncbi.nlm.nih.gov/pubmed/37922210
http://dx.doi.org/10.1021/acssynbio.3c00355

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