Cargando…
Mammalian Genomic Manipulation with Orthogonal Bxb1 DNA Recombinase Sites for the Functional Characterization of Protein Variants
[Image: see text] The Bxb1 bacteriophage serine DNA recombinase is an efficient tool for engineering recombinant DNA into the genomes of cultured cells. Generally, a single engineered “landing pad” site is introduced into the cell genome, permitting the integration of transgenic circuits or librarie...
Autores principales: | Roelle, Sarah M., Kamath, Nisha D., Matreyek, Kenneth A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661055/ https://www.ncbi.nlm.nih.gov/pubmed/37922210 http://dx.doi.org/10.1021/acssynbio.3c00355 |
Ejemplares similares
-
Transgene autoexcision in switchgrass pollen mediated by the Bxb1 recombinase
por: Somleva, Maria N, et al.
Publicado: (2014) -
Crossover-site sequence and DNA torsional stress control strand interchanges by the Bxb1 site-specific serine recombinase
por: Keenholtz, Ross A., et al.
Publicado: (2016) -
Abstract 1390: Multiplex measurements of the impacts of ACE2 sequence and cell surface abundance during SARS-like coronavirus entry
por: Shukla, Nidhi, et al.
Publicado: (2023) -
Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genome
por: Xu, Zhengyao, et al.
Publicado: (2013) -
Targeted integration in CHO cells using CRIS-PITCh/Bxb1 recombinase–mediated cassette exchange hybrid system
por: Ghanbari, Samaneh, et al.
Publicado: (2022)