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A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period

Here, we present a case series of four patients diagnosed with acute ischaemic stroke due to occlusion of the artery of Percheron (AOP), a rare stroke variant, observed in a single emergency centre within a three-month period. AOP occlusion is characterized by bilateral thalamic infarction with or w...

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Autores principales: Perovnik, Matej, Pretnar Oblak, Janja, Frol, Senta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661246/
https://www.ncbi.nlm.nih.gov/pubmed/37987458
http://dx.doi.org/10.3390/neurolint15040085
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author Perovnik, Matej
Pretnar Oblak, Janja
Frol, Senta
author_facet Perovnik, Matej
Pretnar Oblak, Janja
Frol, Senta
author_sort Perovnik, Matej
collection PubMed
description Here, we present a case series of four patients diagnosed with acute ischaemic stroke due to occlusion of the artery of Percheron (AOP), a rare stroke variant, observed in a single emergency centre within a three-month period. AOP occlusion is characterized by bilateral thalamic infarction with or without involvement of the mesencephalon. The presenting symptoms are diverse and not specific, but commonly include disturbance of consciousness, memory impairment, and vertical gaze palsy. In addition, due to the location of the infarction, imaging recognition is challenging and AOP occlusion often remains undiagnosed. This paper emphasizes the necessity of early recognition and appropriate management of AOP occlusion to significantly impact patient outcomes. Moreover, we argue that the condition might be more common than previously thought and that misdiagnosis or delay in diagnosis may lead to inappropriate treatment and potential failure to apply thrombolysis within the required timeframe.
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spelling pubmed-106612462023-11-02 A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period Perovnik, Matej Pretnar Oblak, Janja Frol, Senta Neurol Int Case Report Here, we present a case series of four patients diagnosed with acute ischaemic stroke due to occlusion of the artery of Percheron (AOP), a rare stroke variant, observed in a single emergency centre within a three-month period. AOP occlusion is characterized by bilateral thalamic infarction with or without involvement of the mesencephalon. The presenting symptoms are diverse and not specific, but commonly include disturbance of consciousness, memory impairment, and vertical gaze palsy. In addition, due to the location of the infarction, imaging recognition is challenging and AOP occlusion often remains undiagnosed. This paper emphasizes the necessity of early recognition and appropriate management of AOP occlusion to significantly impact patient outcomes. Moreover, we argue that the condition might be more common than previously thought and that misdiagnosis or delay in diagnosis may lead to inappropriate treatment and potential failure to apply thrombolysis within the required timeframe. MDPI 2023-11-02 /pmc/articles/PMC10661246/ /pubmed/37987458 http://dx.doi.org/10.3390/neurolint15040085 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Perovnik, Matej
Pretnar Oblak, Janja
Frol, Senta
A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title_full A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title_fullStr A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title_full_unstemmed A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title_short A Case Series of Four Patients with Artery of Percheron Occlusion over a Three-Month Period
title_sort case series of four patients with artery of percheron occlusion over a three-month period
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661246/
https://www.ncbi.nlm.nih.gov/pubmed/37987458
http://dx.doi.org/10.3390/neurolint15040085
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