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Anti-Cancer Properties of Flaxseed Proteome

Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These p...

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Autores principales: Merkher, Yulia, Kontareva, Elizaveta, Alexandrova, Anastasia, Javaraiah, Rajesha, Pustovalova, Margarita, Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661269/
https://www.ncbi.nlm.nih.gov/pubmed/37987317
http://dx.doi.org/10.3390/proteomes11040037
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author Merkher, Yulia
Kontareva, Elizaveta
Alexandrova, Anastasia
Javaraiah, Rajesha
Pustovalova, Margarita
Leonov, Sergey
author_facet Merkher, Yulia
Kontareva, Elizaveta
Alexandrova, Anastasia
Javaraiah, Rajesha
Pustovalova, Margarita
Leonov, Sergey
author_sort Merkher, Yulia
collection PubMed
description Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy.
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spelling pubmed-106612692023-11-16 Anti-Cancer Properties of Flaxseed Proteome Merkher, Yulia Kontareva, Elizaveta Alexandrova, Anastasia Javaraiah, Rajesha Pustovalova, Margarita Leonov, Sergey Proteomes Review Flaxseed has been recognized as a valuable source of nutrients and bioactive compounds, including proteins that possess various health benefits. In recent years, studies have shown that flaxseed proteins, including albumins, globulins, glutelin, and prolamins, possess anti-cancer properties. These properties are attributed to their ability to inhibit cancer cell proliferation, induce apoptosis, and interfere with cancer cell signaling pathways, ultimately leading to the inhibition of metastasis. Moreover, flaxseed proteins have been reported to modulate cancer cell mechanobiology, leading to changes in cell behavior and reduced cancer cell migration and invasion. This review provides an overview of the anti-cancer properties of flaxseed proteins, with a focus on their potential use in cancer treatment. Additionally, it highlights the need for further research to fully establish the potential of flaxseed proteins in cancer therapy. MDPI 2023-11-16 /pmc/articles/PMC10661269/ /pubmed/37987317 http://dx.doi.org/10.3390/proteomes11040037 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Merkher, Yulia
Kontareva, Elizaveta
Alexandrova, Anastasia
Javaraiah, Rajesha
Pustovalova, Margarita
Leonov, Sergey
Anti-Cancer Properties of Flaxseed Proteome
title Anti-Cancer Properties of Flaxseed Proteome
title_full Anti-Cancer Properties of Flaxseed Proteome
title_fullStr Anti-Cancer Properties of Flaxseed Proteome
title_full_unstemmed Anti-Cancer Properties of Flaxseed Proteome
title_short Anti-Cancer Properties of Flaxseed Proteome
title_sort anti-cancer properties of flaxseed proteome
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661269/
https://www.ncbi.nlm.nih.gov/pubmed/37987317
http://dx.doi.org/10.3390/proteomes11040037
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