Cargando…
Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature
KEY CLINICAL MESSAGE: Although increasing in number, cases of CVS are being frequently misdiagnosed and many are refractory to the available treatments. This paper draws attention to a timely consideration of this disorder upon suspicion and proposes rectal diazepam and cinnarizine as highly effecti...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661318/ https://www.ncbi.nlm.nih.gov/pubmed/38028097 http://dx.doi.org/10.1002/ccr3.8109 |
_version_ | 1785148465388453888 |
---|---|
author | Togha, Mansoureh Babaei, Mahsa Jameie, Melika |
author_facet | Togha, Mansoureh Babaei, Mahsa Jameie, Melika |
author_sort | Togha, Mansoureh |
collection | PubMed |
description | KEY CLINICAL MESSAGE: Although increasing in number, cases of CVS are being frequently misdiagnosed and many are refractory to the available treatments. This paper draws attention to a timely consideration of this disorder upon suspicion and proposes rectal diazepam and cinnarizine as highly effective treatments in refractory cases of CVS. ABSTRACT: Cyclic vomiting syndrome (CVS) is a set of recurrent episodic attacks of nausea and vomiting. This is a migraine‐related disorder that mostly affects children. Several medications have been recommended for abortive and prophylactic treatment. Unfortunately, in some cases, the treatment is not completely effective and affects the quality of life of the sufferer. In this paper, we report on two cases of children experiencing refractory CVS attacks who were not responsive to recommended medications for acute phase and prophylaxis. This account highlights the efficacy of rectal diazepam for the acute phase of CVS and cinnarizine, an anti‐migraine and anti‐histamine agent, for prophylaxis of further attacks. |
format | Online Article Text |
id | pubmed-10661318 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-106613182023-11-20 Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature Togha, Mansoureh Babaei, Mahsa Jameie, Melika Clin Case Rep Case Series KEY CLINICAL MESSAGE: Although increasing in number, cases of CVS are being frequently misdiagnosed and many are refractory to the available treatments. This paper draws attention to a timely consideration of this disorder upon suspicion and proposes rectal diazepam and cinnarizine as highly effective treatments in refractory cases of CVS. ABSTRACT: Cyclic vomiting syndrome (CVS) is a set of recurrent episodic attacks of nausea and vomiting. This is a migraine‐related disorder that mostly affects children. Several medications have been recommended for abortive and prophylactic treatment. Unfortunately, in some cases, the treatment is not completely effective and affects the quality of life of the sufferer. In this paper, we report on two cases of children experiencing refractory CVS attacks who were not responsive to recommended medications for acute phase and prophylaxis. This account highlights the efficacy of rectal diazepam for the acute phase of CVS and cinnarizine, an anti‐migraine and anti‐histamine agent, for prophylaxis of further attacks. John Wiley and Sons Inc. 2023-11-20 /pmc/articles/PMC10661318/ /pubmed/38028097 http://dx.doi.org/10.1002/ccr3.8109 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Series Togha, Mansoureh Babaei, Mahsa Jameie, Melika Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title | Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title_full | Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title_fullStr | Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title_full_unstemmed | Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title_short | Good response to rectal diazepam in refractory cases of cyclic vomiting: A case‐series and review of the literature |
title_sort | good response to rectal diazepam in refractory cases of cyclic vomiting: a case‐series and review of the literature |
topic | Case Series |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661318/ https://www.ncbi.nlm.nih.gov/pubmed/38028097 http://dx.doi.org/10.1002/ccr3.8109 |
work_keys_str_mv | AT toghamansoureh goodresponsetorectaldiazepaminrefractorycasesofcyclicvomitingacaseseriesandreviewoftheliterature AT babaeimahsa goodresponsetorectaldiazepaminrefractorycasesofcyclicvomitingacaseseriesandreviewoftheliterature AT jameiemelika goodresponsetorectaldiazepaminrefractorycasesofcyclicvomitingacaseseriesandreviewoftheliterature |