A CRISPR-Cas9 library screening identifies CARM1 as a critical inhibitor of ferroptosis in hepatocellular carcinoma cells

Ferroptosis is an iron-catalyzed form of regulated cell death that results from the accumulation of lipid peroxidation products and reactive oxygen species to a lethal content. However, the transcriptional regulation of ferroptosis is not well understood. Sorafenib, a standard drug for hepatocellula...

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Detalles Bibliográficos
Autores principales: Cheng, Yiming, Wang, Xiaochen, Huang, Shuyu, Zhang, Liang, Lan, Bei, Li, Xuanyuan, Chen, Hao, Liu, Zhenfeng, Su, Yijie, Xi, Lishan, Feng, Shengyun, Guo, Yanxuan, Zhou, Jun, Wang, Yingmei, Xuan, Chenghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661451/
https://www.ncbi.nlm.nih.gov/pubmed/38028203
http://dx.doi.org/10.1016/j.omtn.2023.102063

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661451/
https://www.ncbi.nlm.nih.gov/pubmed/38028203
http://dx.doi.org/10.1016/j.omtn.2023.102063

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