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A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications
3D printing technology is an emerging method that gained extensive attention from researchers worldwide, especially in the health and medical fields. Biopolymers are an emerging class of materials offering excellent properties and flexibility for additive manufacturing. Biopolymers are widely used i...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661719/ https://www.ncbi.nlm.nih.gov/pubmed/37982917 http://dx.doi.org/10.1007/s10856-023-06765-9 |
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author | S, Shiva R G, Asuwin Prabu Bajaj, Gauri John, Amy Elsa Chandran, Sharan Kumar, Vishnu Vijay Ramakrishna, Seeram |
author_facet | S, Shiva R G, Asuwin Prabu Bajaj, Gauri John, Amy Elsa Chandran, Sharan Kumar, Vishnu Vijay Ramakrishna, Seeram |
author_sort | S, Shiva |
collection | PubMed |
description | 3D printing technology is an emerging method that gained extensive attention from researchers worldwide, especially in the health and medical fields. Biopolymers are an emerging class of materials offering excellent properties and flexibility for additive manufacturing. Biopolymers are widely used in biomedical applications in biosensing, immunotherapy, drug delivery, tissue engineering and regeneration, implants, and medical devices. Various biodegradable and non-biodegradable polymeric materials are considered as bio-ink for 3d printing. Here, we offer an extensive literature review on the current applications of synthetic biopolymers in the field of 3D printing. A trend in the publication of biopolymers in the last 10 years are focused on the review by analyzing more than 100 publications. Their application and classification based on biodegradability are discussed. The various studies, along with their practical applications, are elaborated in the subsequent sections for polyethylene, polypropylene, polycaprolactone, polylactide, etc. for biomedical applications. The disadvantages of various biopolymers are discussed, and future perspectives like combating biocompatibility problems using 3D printed biomaterials to build compatible prosthetics are also discussed and the potential application of using resin with the combination of biopolymers to build customized implants, personalized drug delivery systems and organ on a chip technologies are expected to open a new set of chances for the development of healthcare and regenerative medicine in the future. GRAPHICAL ABSTRACT: [Image: see text] |
format | Online Article Text |
id | pubmed-10661719 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-106617192023-11-20 A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications S, Shiva R G, Asuwin Prabu Bajaj, Gauri John, Amy Elsa Chandran, Sharan Kumar, Vishnu Vijay Ramakrishna, Seeram J Mater Sci Mater Med Clinical Applications of Biomaterials 3D printing technology is an emerging method that gained extensive attention from researchers worldwide, especially in the health and medical fields. Biopolymers are an emerging class of materials offering excellent properties and flexibility for additive manufacturing. Biopolymers are widely used in biomedical applications in biosensing, immunotherapy, drug delivery, tissue engineering and regeneration, implants, and medical devices. Various biodegradable and non-biodegradable polymeric materials are considered as bio-ink for 3d printing. Here, we offer an extensive literature review on the current applications of synthetic biopolymers in the field of 3D printing. A trend in the publication of biopolymers in the last 10 years are focused on the review by analyzing more than 100 publications. Their application and classification based on biodegradability are discussed. The various studies, along with their practical applications, are elaborated in the subsequent sections for polyethylene, polypropylene, polycaprolactone, polylactide, etc. for biomedical applications. The disadvantages of various biopolymers are discussed, and future perspectives like combating biocompatibility problems using 3D printed biomaterials to build compatible prosthetics are also discussed and the potential application of using resin with the combination of biopolymers to build customized implants, personalized drug delivery systems and organ on a chip technologies are expected to open a new set of chances for the development of healthcare and regenerative medicine in the future. GRAPHICAL ABSTRACT: [Image: see text] Springer US 2023-11-20 2023 /pmc/articles/PMC10661719/ /pubmed/37982917 http://dx.doi.org/10.1007/s10856-023-06765-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Clinical Applications of Biomaterials S, Shiva R G, Asuwin Prabu Bajaj, Gauri John, Amy Elsa Chandran, Sharan Kumar, Vishnu Vijay Ramakrishna, Seeram A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title | A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title_full | A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title_fullStr | A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title_full_unstemmed | A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title_short | A review on the recent applications of synthetic biopolymers in 3D printing for biomedical applications |
title_sort | review on the recent applications of synthetic biopolymers in 3d printing for biomedical applications |
topic | Clinical Applications of Biomaterials |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661719/ https://www.ncbi.nlm.nih.gov/pubmed/37982917 http://dx.doi.org/10.1007/s10856-023-06765-9 |
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