Immunologic and Genetic Contributors to CD46-Dependent Immune Dysregulation

Mutations in CD46 predispose to atypical hemolytic uremic syndrome (aHUS) with low penetrance. Factors driving immune-dysregulatory disease in individual mutation carriers have remained ill-understood. In addition to its role as a negative regulator of the complement system, CD46 modifies T cell-int...

Descripción completa

Detalles Bibliográficos
Autores principales: Meyer, Benedikt J, Kunz, Natalia, Seki, Sayuri, Higgins, Rebecca, Ghosh, Adhideb, Hupfer, Robin, Baldrich, Adrian, Hirsiger, Julia R, Jauch, Annaïse J, Burgener, Anne-Valérie, Lötscher, Jonas, Aschwanden, Markus, Dickenmann, Michael, Stegert, Mihaela, Berger, Christoph T, Daikeler, Thomas, Heijnen, Ingmar, Navarini, Alexander A, Rudin, Christoph, Yamamoto, Hiroyuki, Kemper, Claudia, Hess, Christoph, Recher, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661731/
https://www.ncbi.nlm.nih.gov/pubmed/37477760
http://dx.doi.org/10.1007/s10875-023-01547-y

Ejemplares similares

Ejemplares similares