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Cytotoxic pathways activated by multifunctional thiosemicarbazones targeting sigma-2 receptors in breast and lung carcinoma cells

BACKGROUND: Multifunctional thiosemicarbazones (TSCs) able to bind sigma receptors and chelate metals are considered as a promising avenue for the treatment of pancreatic cancer due to the encouraging results obtained on in vitro and in vivo models. Here, we assessed the biochemical mechanism of the...

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Detalles Bibliográficos
Autores principales:	Kopecka, Joanna, Barbanente, Alessandra, Vitone, Daniele, Arnesano, Fabio, Margiotta, Nicola, Berchialla, Paola, Niso, Mauro, Riganti, Chiara, Abate, Carmen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661773/ https://www.ncbi.nlm.nih.gov/pubmed/37796435 http://dx.doi.org/10.1007/s43440-023-00531-y

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