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The effect of brain serotonin deficit (TPH2-KO) on the expression and activity of liver cytochrome P450 enzymes in aging male Dark Agouti rats

BACKGROUND: Liver cytochrome P450 (CYP) greatly contributes to the metabolism of endogenous substances and drugs. Recent studies have demonstrated that CYP expression in the liver is controlled by the central nervous system via hormonal pathways. In particular, the expression of hepatic CYPs is nega...

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Detalles Bibliográficos
Autores principales:	Haduch, Anna, Bromek, Ewa, Kuban, Wojciech, Basińska-Ziobroń, Agnieszka, Danek, Przemysław J., Alenina, Natalia, Bader, Michael, Daniel, Władysława A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661807/ https://www.ncbi.nlm.nih.gov/pubmed/37848703 http://dx.doi.org/10.1007/s43440-023-00540-x

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