Cargando…

Accelerated Extracellular Nucleotide Metabolism in Brain Microvascular Endothelial Cells in Experimental Hypercholesterolemia

Hypercholesterolemia affects the neurovascular unit, including the cerebral blood vessel endothelium. Operation of this system, especially in the context of energy metabolism, is controlled by extracellular concentration of purines, regulated by ecto-enzymes, such as e-NTPDase-1/CD39, ecto-5′-NT/CD7...

Descripción completa

Detalles Bibliográficos
Autores principales:	Czuba-Pakuła, Ewelina, Pelikant-Małecka, Iwona, Lietzau, Grażyna, Wójcik, Sławomir, Smoleński, Ryszard T., Kowiański, Przemysław
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10661815/ https://www.ncbi.nlm.nih.gov/pubmed/37801200 http://dx.doi.org/10.1007/s10571-023-01415-8

Ejemplares similares

Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions
por: Czuba, Ewelina, et al.
Publicado: (2017)

More than Addiction—The Nucleus Accumbens Contribution to Development of Mental Disorders and Neurodegenerative Diseases
por: Bayassi-Jakowicka, Martyna, et al.
Publicado: (2022)

BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity
por: Kowiański, Przemysław, et al.
Publicado: (2017)

Neurovascular Unit as a Source of Ischemic Stroke Biomarkers—Limitations of Experimental Studies and Perspectives for Clinical Application
por: Steliga, Aleksandra, et al.
Publicado: (2019)

Neuroplasticity and Multilevel System of Connections Determine the Integrative Role of Nucleus Accumbens in the Brain Reward System
por: Bayassi-Jakowicka, Martyna, et al.
Publicado: (2021)

Hidden Pool of Cardiac Adenine Nucleotides That Controls Adenosine Production
por: Zabielska-Kaczorowska, Magdalena A., et al.
Publicado: (2023)

The Effect of Simvastatin on the Dynamics of NF-κB-Regulated Neurodegenerative and Neuroprotective Processes in the Acute Phase of Ischemic Stroke
por: Lietzau, Grazyna, et al.
Publicado: (2023)

Neuroprotective Effects of Guanosine in Ischemic Stroke—Small Steps towards Effective Therapy
por: Chojnowski, Karol, et al.
Publicado: (2021)

Neuroprotective effect of masitinib in rats with postischemic stroke
por: Kocic, Ivan, et al.
Publicado: (2014)

An unusual nicotinamide derivative, 4-pyridone-3-carboxamide ribonucleoside (4PYR), is a novel endothelial toxin and oncometabolite
por: Mierzejewska, Paulina, et al.
Publicado: (2021)

Adenosine deaminase inhibition suppresses progression of 4T1 murine breast cancer by adenosine receptor‐dependent mechanisms
por: Kutryb‐Zajac, Barbara, et al.
Publicado: (2018)

Hypercholesterolemia and microvascular dysfunction: interventional strategies
por: Stapleton, Phoebe A, et al.
Publicado: (2010)

Proteomic and Metabolomic Changes in Psoriasis Preclinical and Clinical Aspects
por: Radulska, Adrianna, et al.
Publicado: (2023)

Hepatocyte nuclear factors as possible C-reactive protein transcriptional inducer in the liver and white adipose tissue of rats with experimental chronic renal failure
por: Sucajtys-Szulc, Elzbieta, et al.
Publicado: (2018)

CoCl(2)-Mimicked Endothelial Cell Hypoxia Induces Nucleotide Depletion and Functional Impairment That Is Reversed by Nucleotide Precursors
por: Kutryb-Zajac, Barbara, et al.
Publicado: (2022)

Western Diet Accelerates the Impairment of Odor-Related Learning and Olfactory Memory in the Mouse
por: Lietzau, Grazyna, et al.
Publicado: (2020)

Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
por: Cichorek, Miroslawa, et al.
Publicado: (2018)

Reversal of MK-801-Induced Disruptions in Social Interactions and Working Memory with Simultaneous Administration of LY487379 and VU152100 in Mice
por: Cieślik, Paulina, et al.
Publicado: (2019)

Blocking cholesterol formation and turnover improves cellular and mitochondria function in murine heart microvascular endothelial cells and cardiomyocytes
por: Braczko, Alicja, et al.
Publicado: (2023)

Purine Nucleotides Metabolism and Signaling in Huntington’s Disease: Search for a Target for Novel Therapies
por: Tomczyk, Marta, et al.
Publicado: (2021)

P050: Reed-Sternberg cells accelerate glycolytic and mitochondrial metabolism of tumor microenvironment cells
por: Kurlapski, Michał, et al.
Publicado: (2022)

Melanization as unfavorable factor in amelanotic melanoma cell biology
por: Skoniecka, A., et al.
Publicado: (2021)

GABA-A receptor genes do not play a role in genetics of Lesch's typology in Caucasian subjects
por: Grzywacz, Anna, et al.
Publicado: (2012)

New Insight into Plant Signaling: Extracellular ATP and Uncommon Nucleotides
por: Pietrowska-Borek, Małgorzata, et al.
Publicado: (2020)

Retinal Microvascular Changes in Familial Hypercholesterolemia: Analysis with Swept-Source Optical Coherence Tomography Angiography
por: Eid, Pétra, et al.
Publicado: (2022)

Nucleotide metabolic mismatches in mammalian hearts: implications for transplantation
por: Khalpey, Z, et al.
Publicado: (2013)

Differences in Extracellular NAD(+) and NMN Metabolism on the Surface of Vascular Endothelial Cells
por: Jablonska, Patrycja, et al.
Publicado: (2022)

Cyclic nucleotide‐dependent inhibitory signaling interweaves with activating pathways to determine platelet responses
por: Nagy, Zoltan, et al.
Publicado: (2018)

Trimethylamine N-oxide and the reverse cholesterol transport in cardiovascular disease: a cross-sectional study
por: Bordoni, Laura, et al.
Publicado: (2020)

Hypercholesterolemia Induces Oxidant Stress That Accelerates the Ageing of Hematopoietic Stem Cells
por: Tie, Guodong, et al.
Publicado: (2014)

Porcine Models of Accelerated Coronary Atherosclerosis: Role of Diabetes Mellitus and Hypercholesterolemia
por: Hamamdzic, Damir, et al.
Publicado: (2013)

Comparison of some secondary metabolite content in the seventeen species of the Boraginaceae family
por: Dresler, Sławomir, et al.
Publicado: (2017)

HILIC-MS Rat Brain Analysis, A New Approach for the Study of Ischemic Attack
por: Miękus, Natalia, et al.
Publicado: (2017)

Management of Familial Hypercholesterolemia with Special Emphasis on Evinacumab
por: Krzemińska, Julia, et al.
Publicado: (2022)

Effect of decaffeinated coffee on function and nucleotide metabolism in kidney
por: Rybakowska, I. M., et al.
Publicado: (2017)

Genetics of Hypercholesterolemia: Comparison Between Familial Hypercholesterolemia and Hypercholesterolemia Nonrelated to LDL Receptor
por: Jarauta, Estíbaliz, et al.
Publicado: (2020)

Cyclic Nucleotide Dependent Dephosphorylation of Regulator of G-Protein Signaling 18 in Human Platelets
por: Gegenbauer, Kristina, et al.
Publicado: (2013)

Diet Induced Mild Hypercholesterolemia in Pigs: Local and Systemic Inflammation, Effects on Vascular Injury – Rescue by High-Dose Statin Treatment
por: Busnelli, Marco, et al.
Publicado: (2013)

Genetically confirmed familial hypercholesterolemia in outpatients with hypercholesterolemia
por: Wang, Xu, et al.
Publicado: (2018)

Improved extracellular vesicle-based mRNA delivery for familial hypercholesterolemia treatment
por: Yang, Zheng, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3v56u5tcvhrgg27nko4ncrobsq